Subcutaneous Fat in Liver Cirrhosis

Document Type : Original Article

Authors

1 Pediatric Department, Ahmed Maher Teaching Hospital

2 Hepatology Department Ahmed Maher Teaching Hospital

3 Community Department Cairo University

Abstract

We have studied the degree of disturbance of fat metabolism represented by the thickness of subcutaneous fat and the degree of liver impairment according to Child Pugh's grading. The mean (+_SD) subcutaneous normal fat in the control, Child A, Child B, and Child C were 16,05+- 0.43;14.25+- 0.21; 11,06 +- 0.51 and 8.18 +- 0.42 respectively. The mean subcutaneous fat was significantly affected especially in patients classified as Child C (P < 0.0001).Same finding was found in considering serum albumin and serum bilirubin. The decreased subcutaneous fat statistically was significantly correlated with elevated serum bilirubin especially in patient classified as Child C and B, (P < 0.0001). This study concludes that the ultrasonographic measurement of subcutaneous fat thickness is a sensitive, reliable and valid method of evaluating the nutritional status and detecting wasting of adipose tissue which occurs in severe liver cirrhosis.